Principal Clinical Scientist

Principal Clinical Scientist (AI Training)

About The Role

What if your years of clinical trial expertise could directly shape how AI reasons about biomedical evidence — influencing systems that will impact research and patient outcomes for years to come?

We're looking for a Principal Clinical Scientist to bring senior-level rigor into cutting-edge AI development. You'll work alongside world-leading AI research teams, ensuring that the clinical data and reasoning embedded in frontier AI models meets the standards you'd expect in a real-world regulatory submission.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work on their own terms.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready training datasets
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations (FDA, EMA, or equivalent)
• Provide expert, structured feedback that directly improves how AI models reason about clinical trial data and outcomes
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level experience designing clinical trial protocols intended for regulatory submission
• Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent bodies
• Strong command of clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold your work to the same standards regulators do
• Clear, structured communicator who can articulate complex scientific reasoning in writing

Nice to Have

• Prior experience with data annotation, data quality review, or evaluation systems
• Background in AI-adjacent roles such as digital health, clinical decision support, or health informatics
• Familiarity with how AI systems are trained and evaluated

Why Join Us

• Work directly on frontier AI systems shaping the future of clinical and biomedical research
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, high-impact work
• Collaborate with leading AI research teams and labs globally
• Potential for ongoing work and contract extension as new projects launch